Under the right conditions, our high-pressure homogenizers can reduce particle sizes to smaller than 100 nm. However, the outcome depends on the material's initial particle size, hardness, and viscosity. Softer materials with smaller initial particles are more likely to achieve finer-sized particles as a result.

Pricing depends on your requirements and needs. To provide a suitable model and an accurate quotation, we will first confirm some specifications that directly affect the homogenizer's configuration and overall cost, such as:

• Your required output capacity (L/H);
• Material characteristics (e.g., corrosive, high-temperature, sensitive components, and more);
• Whether optional features are needed (CIP cleaning system, cooling system, explosion-proof design, etc.).

The main wear parts of the high-pressure homogenizer are designed for simple and quick replacement as part of routine maintenance. These parts include plunger seal rings, homogenizing valve components (valve core and seat), and high-pressure seals. The homogenizers adopt a modular design, allowing wear parts to be replaced with basic tools like a hex key and a torque wrench, without disassembling the entire machine. In addition, all special tools and detailed instruction videos are provided, and our engineers offer real-time remote guidance during replacement.

Yes. ATS supports customized sterile homogenizer solutions. All homogenizers are designed according to GMP standards and can achieve automated production through a PLC control system, fully meeting the requirements of sterile workshop operations.

The industrial-scale high-pressure homogenizers are equipped with a variable flow control system that allows flexible flow adjustment within 100-4000 L/H without needing to replace any core components.

No. The laboratory scale homogenizer is easy to operate, requiring no special training. It is equipped with an intuitive, user-friendly 7-inch touchscreen with a high-resolution color display that shows pressure trend graphs and alarm information.

The laboratory high-pressure homogenizer is equipped with a built-in temperature control system to manage the temperature during processing effectively. Some homogenizer models, such as the AH-1500, also feature enhanced cooling performance to prevent heat-induced denaturation.

The laboratory scale high-pressure homogenizer is motor-driven. The high-pressure plunger pump will pressurize the sample and force it into a narrow valve with a significant pressure difference up to 2000 bar. The energy generated by the instant drop in pressure achieves homogenization, dispersion, and disruption.

Yes. ATS's high-pressure pilot-scale homogenizers have a minimum volume of 50 ml, making them suitable for laboratory-scale processing, and a capacity of 100 L/H that satisfies pilot-scale processing requirements. The homogenizers are also GMP-compliant and CE-certified, meeting the transition needs of the biopharmaceutical industry.

Yes. The pilot-scale high-pressure homogenizer supports additional upgrades of two-stage homogenization and PLC control system.

Yes. The pilot-scale high-pressure homogenizer is equipped with a 5.5kW motor and can handle materials with viscosity <2000cP and particle size <500μm. And the flow rate ranges from 20 to 100 L/H, suitable for laboratory and pilot-scale production needs.

Yes. ATS industrial homogenizer features a rapid heat exchange system that effectively controls temperature rise during the homogenization process. This helps preserve biological activity.

ATS industrial-scale high-pressure homogenizer features a special feed valve design that supports smooth, direct feeding without venting, suitable for both low- and high-viscosity materials. It is also adaptable to a wide range of materials, thus avoiding feeding obstructions or jams.

Yes. ATS industrial-scale homogenizer supports PLC control for automated production and can be integrated with your existing DCS system in the workshop.

The diamond interaction chamber (DIXC) in the micro-jet homogenizer allows linear scale-up production by arranging multiple identical microchannels in parallel. The industrial and laboratory scales homogenizer uses the same configurations to achieve linear scaling with the same homogenization results.

Yes. All wetted parts (pump, chamber, pipelines) are easily detachable. The micro-jet homogenizer supports autoclave sterilization and CIP cleaning, enabling quick cleaning and sterilizing processes and preventing cross-contamination.

The standard configuration of the laboratory micro-jet homogenizer supports CIP cleaning. While the SIP sterilization is available through customization to ensure it meets the high aseptic requirements, such as vaccine research and development.

Yes. All wetted parts (pump, chamber, pipelines) support autoclaved or Clean In Place (CIP) cleaning, and optional Sterilization-in-Place (SIP) can be customized to meet stringent aseptic environment standards.

The pilot-scale micro-jet homogenizers utilize diamond interaction chamber (DIXC) ultra-high-speed jet technology to produce finer, more uniform nano-scale dispersion. It also includes hydraulic pressure intensification, which reduces failure rates and improves operational stability.

Compared to the regular high-pressure homogenizer, the micro-jet homogenizer adopts the hydraulic intensifier instead of the ultrasonic connecting rod. The hydraulic intensifier generates high homogenization pressure at low pressure. It is also combined with automatic lubrication for shaft components and servo control, which enhances wear resistance and ensures long-term continuous operation.

Through the fixed-size diamond interaction chambers (DIXC), hydraulic intensifier, and reinforced structure, this industrial homogenizer ensures a stable output and consistent nano-level dispersion under 30,000 psi. This ensures continuous operation with nano-size precision and more uniform homogenization for each batch, especially for food & beverage, pharmaceutical, and other industries.

The industrial-scale homogenizer utilizes a diamond interaction chamber under a stable 207 MPa pressure. The chamber's ultra-high-speed jet technology enhances the shearing and turbulent forces, while the wear-resistant diamond material ensures nano-scale homogenization when processing hard materials, minimizing component wear.

Compared to regular high-pressure homogenizers, the industrial micro-jet homogenizers can avoid the scale-up production risks. It uses a multiple microchannel parallel design and the diamond interaction chamber ultra-high-speed jet technology to achieve linear scale-up without altering the homogenization performance.

The laboratory liposome extruder uses a jacketed temperature-control system (NF-1 model uses water-bath heating) to maintain a stable sample temperature between 5–80°C. Temperature control is applied both before and after extrusion to prevent thermal fluctuation and ensure sample stability for temperature-sensitive samples.

All wetted pipelines are made of 316L stainless steel with 1.5 Ra electropolished surfaces, and FDA-certified components (e.g., O-rings), ensuring high cleanliness, easy sterilization, and virtually no dead-volume or cross-contamination.

The jacketed extrusion is equipped with a built-in pressure safety valve (up to 1000 psi) that maintains constant pressure during repeated extrusion through polycarbonate membranes. The 316L stainless-steel pipelines and mirror-polished filter plates reduce material retention, ensuring high extrusion efficiency and liposome uniformity between 50–1000 nm.

The extrusion plate and all wetted parts are made of sanitary-grade 316L stainless steel (FDA-certified O-rings included). The system supports CIP and SIP cleaning and can be used in cleanrooms. It also provides validation documentation (certificates and drawings) to support GMP verification.

The extrusion plate uses 316L stainless steel with laser-drilled microporous support plates and built-in pressure control (0–7500 psi) to prevent overpressure damage. This extrusion also supports CIP cleaning to reduce corrosion caused by material residue, ensuring stable long-term operation.

Yes. The system supports compatibility and scalability. By changing filter membranes of different pore sizes or adding more extrusion plates and pump upgrades (e.g., from electric to high-pressure homogenizer), users can expand production capacity or adapt to new liposome formulations without replacing the main system.