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Pilot Scale Micro-Jet Homogenizer (Microfluidic Homogenizer)
High Pressure Homogenizer

Pilot Scale Micro-Jet Homogenizer (Microfluidic Homogenizer)

High shear fluid processor bridging the gap between lab R&D and industrial production, ensuring uniform nanoparticle size distribution

ATS pilot-scale micro-jet homogenizer bridging the gap between laboratory research and industrial production. This homogenizer operates stably at pressures up to 40,000 psi, with diamond interaction chamber (DIXC) technology to achieve precise nano-level homogenization with ultra-narrow particle-size distribution, perfectly reproducing the lab-scale data. Its adjustable flow rate supports scale-up production, parameter optimization, and designed for mid to small-batch production, while reducing cost and risk during industrialization.

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Product Specifications
Models AMH-M30 AMH-M60
Flow Rate (L/H) 30 50-60
Min. Volume (ml) 200 300
Max. Working Pressure 207 MPa/2070 bar/30,000 psi 207 MPa/2070 bar/30,000 psi
Chamber Configurations Main 200um + auxiliary 75um Y/Z-type DIXC Main 400um + auxiliary 75um Y/Z-type DIXC
Operation Mode 380V hydraulic 380V hydraulic
Power (kW) 7.5 11
Dimensions (mm) 1400*450*475 1600*840*1520
Features
  • This micro-jet homogenizer is a new generation of high-pressure homogenizer, using unique diamond microchannel ultra-high-speed jet technology to achieve smaller and more uniform nano-scale particle sizes homogenization compared with ordinary high-pressure homogenizers. This micro-jet homogenizer is ideal for high-value applications requiring uniform nano-scale particle sizes across various industries.
  • Utilizing Diamond Interaction Chamber (DIXC) as the core component of the micro-jet homogenizer. Unlike regular high-pressure homogenizers with adjustable gap valves, the microchannels within DIXC are of fixed size and cannot be altered. Consequently, the micro-jet homogenizer can maintain consistent homogenization conditions, facilitating the production of uniform-sized nanoparticles that ensure highly stable results across batches under consistent process parameters.
  • Linear scale-up production involves arranging multiple identical microchannels in parallel within the diamond interaction chamber of a micro-jet homogenizer. By using multiple microchannels with the same performance as those in lab-scale homogenizers and employing a high-power intensifier pump, the R&D process can be scaled linearly. This allows industrial-scale homogenizers to increase output without changing the homogenization quality, a feat difficult for standard high-pressure homogenizers. As a result, many high-requirement scenarios choose micro-jet homogenizers to avoid scale-up production problems after successful, costly labo-scale testing.
  • The micro-jet homogenizer uses hydraulic pressure intensification to generate homogenization power. Its hydraulic power unit can produce very high homogenization pressures (hundreds of MPa) while operating at relatively low hydraulic pressures (a minimum of dozens of MPa). Under these conditions, the hydraulic power unit can run continuously and stably while still providing very high homogenization pressure. Compared to the complex high-frequency ultrasonic homogenizer with a connecting rod design used in ordinary high-pressure homogenizers, the hydraulic intensification system greatly reduces the equipment's failure rate, ensuring smooth and uninterrupted production.
Working Principle
Working Principle

The fluid sample is rapidly forced through the narrow gaps within the dispersion unit under high pressure. The sudden pressure drops generate extremely high-speed velocities, leading to intense turbulence, cavitation, shear forces, and jet flow, which break apart the particles, reducing them into a fine and uniform nano-scale homogeneous state. Furthermore, the hydraulic intensifier power mode can provide a stable pressure of up to 200 MPa.

Turbulence

Turbulence
Turbulence is caused by the mutual collisions of sample molecules due to cavitation.

Shearing

Shearing
Shearing in fluids occurs due to the friction between the molecules and the wall of the dispersion unit, viscosity, etc.

Cavitation

Cavitation
Cavitation refers to the cavities or bubbles created in fluids. If the velocity increases, the cohesive force between molecules and the voids or bubbles in the liquid rapidly collapses, generating a shock wave.

Our Micro-Jet Homogenizer
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Yes. All wetted parts (pump, chamber, pipelines) support autoclaved or Clean In Place (CIP) cleaning, and optional Sterilization-in-Place (SIP) can be customized to meet stringent aseptic environment standards.

The pilot-scale micro-jet homogenizers utilize diamond interaction chamber (DIXC) ultra-high-speed jet technology to produce finer, more uniform nano-scale dispersion. It also includes hydraulic pressure intensification, which reduces failure rates and improves operational stability.

Compared to the regular high-pressure homogenizer, the micro-jet homogenizer adopts the hydraulic intensifier instead of the ultrasonic connecting rod. The hydraulic intensifier generates high homogenization pressure at low pressure. It is also combined with automatic lubrication for shaft components and servo control, which enhances wear resistance and ensures long-term continuous operation.